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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: Gastroenterology. 2019 May 17;157(3):731–743. doi: 10.1053/j.gastro.2019.05.010

Figure 2.

Figure 2.

Association of decreased HuR with a reduction in Paneth cells in the intestinal mucosa of patients with inflammatory bowel disease (IBD). (A) Immunohistochemical staining of HuR in the ileum mucosa from control individuals (without mucosal erosions/inflammation) and patients with IBD. Green, HuR; blue, nucleus stained by DAPI. Scale bars, 25 μm. (B) Immunostaining of HuR in the colon mucosa in control individuals and IBD patients. Red, HuR; purple, nucleus stained by DAPI. (C) Immunostaining of ileum paraffin section with anti-lysozyme (red), anti-E-cadherin (green), and DAPI (blue). All these experiments were repeated in human tissue samples obtained from four control individuals or patients with IBD and showed similar results.