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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: Gastroenterology. 2019 May 17;157(3):731–743. doi: 10.1053/j.gastro.2019.05.010

Figure 3.

Figure 3.

HuR knockout disrupts the subcellular distribution of TLR2 in the small intestinal epithelium in vivo and ex vivo. (A) Immunostaining of the small intestinal mucosa with anti-TLR2 (red), anti-E-cadherin (E-cad, green), and DAPI (blue) in mice. Scale bars, 25 μm. The experiments were repeated in the mucosal tissues obtained from three control littermates or IE-HuR−/− mice and showed similar results. (B) Immunostaining of TLR2 and E-cadherin in the intestinal organoids isolated from control littermate and IE-HuR−/− mice. In images shown in right two panels, TLR2 fluorescence was merged with E-cadherin and DIC images, respectively. Scale bars, 100 μm.