Figure 2: Main Effect of Insulin Resistance on MWF.
Main Effect of Insulin Resistance on MWF- Multislice rendering of statistically significant results relating IR and MWF. Negative relationships are shown in blue and positive relationships in red, overlaid on the MNI template. For visualization, scatter plots show the overall association between mean MWF and HOMA-IR from the significant clusters. Regions where a negative association between MWF and HOMA-IR were observed localized in myelinated bilateral regions of the parieto-occipiatal projections of the corpus callosum and white matter surrounding the cuneus. Regions exhibiting a positive association between MWF and HOMA-IR localized in cortical regions, including frontal, occipital and temporal cortices.