TABLE 1.

Genes encoding potential and confirmed nucleases in the genome of P. aeruginosa PAO1^a

PA number	Gene name	Localization	N-terminal signal	Description
PA0965	ruvC	Cytoplasmic	None	Holliday junction resolvase
PA2545	xthA	Cytoplasmic	None	Exonuclease III
PA2585	uvrC	Cytoplasmic	None	Endonuclease
PA2749	endA	Extracellular	Type I	Endonuclease, DNA-specific endonuclease I
PA3232	PA3232	Cytoplasmic	None	Probable nuclease
PA3495	Nth	Cytoplasmic	None	Endonuclease III
PA3725	recJ	Cytoplasmic	None	Single-stranded-DNA-specific exonuclease
PA3909	eddB	Extracellular	Type I	Extracellular DNA degradation protein
PA3910	eddA	Extracellular	Type I	Alkaline phosphatase, PhoD-type phosphataseb
PA4172	PA4172	Cytoplasmic	None	Probable nuclease, endonuclease III-like
PA4281	sbcD	Cytoplasmic	None	Exonuclease
PA4316	scbB	Cytoplasmic	None	Exodeoxyribonuclease I, exonuclease I
PA4424	PA4424	Unknown	None	Endonuclease II-like (yraN homolog)
PA5048	PA5048	Unknown	None	Probable nuclease, SNase-like
PA5147	mutY	Cytoplasmic		Endonuclease, endonuclease III-like

^aUnless otherwise noted, localizations and descriptions were adopted from pseudomonas.com (41), while predictions of N-terminal signals were obtained from Lewenza et al. (42).

^bDescription adopted from references 45 and 46.