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. 2019 Aug 2;36(8):1561–1569. doi: 10.1007/s10815-019-01501-1

Table 2.

Comparison of time-lapse morphokinetic parameters of the earlier stages of embryonic development between day 5 and day 6 blastocysts

TLM parameters Day 5 blastocysts Day 6 blastocysts
Mean Std. err Std. dev CI 95% Mean Std. err Std. dev CI 95% p value
tPNf 23.1 0.07 2.8 23.0–23.2 24.8 0.15 3.3 24.5–25.1 > 0.000
t2 25.7 0.13 5.5 25.5–26.0 27.2 0.16 3.4 26.9–27.6 > 0.000
t3 35.9 0.10 3.9 35.7–36.1 38.1 0.25 5.1 37.6–38.6 > 0.000
t4 37.5 0.97 4.1 37.4–37.7 40.5 0.27 5.7 40.0–41.1 > 0.000
t5 48.6 0.15 6.0 48.3–48.9 52.0 0.42 8.6 51.2–52.8 > 0.000
t6 51.3 0.14 5.7 51.1–51.6 56.1 0.38 7.9 55.4–56.9 > 0.000
t7 54.3 0.17 6.8 54.0–54.7 60.7 0.47 9.4 59.8–61.6 > 0.000
t8 59.4 0.23 8.9 58.9–59.8 65.7 0.55 10.9 64.6 > 0.000

tPNf = pronuclei faded; t2, t3, t4, t5, t6, t7, t8 = time between intracytoplasmic injection and 2-, 3-, 4-, 5-, 6-, 7-, and 8-cell stages, respectively