Table 4.

Diagnostic accuracy measures in non-contrast-enhanced MRI techniques and contrast-enhanced techniques in brain infection

Clinical question	Diagnostic performance non-CE	Diagnostic performance CE gold standard	Author (year)
Abscess detection	Specificity 100% ADC	CE T1 and T2 signal intensity could not distinguish between groups	Nadal et al. (2003)
Detecting infectious meningitis	Sensitivity 33% T2 FLAIR	Sensitivity 100% T2 FLAIR	Splendiani et al. (2005)
Detecting infectious meningitis	Sensitivity 25% 3DT2FLAIR	Sensitivity 75% CE 3DT2FLAIR	Fukuoka et al. (2010)

ADC apparent diffusion coefficient, AUC area under curve, CE contrast-enhanced, FLAIR fluid attenuated inversion recovery