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Examples of engineering techniques to control in vivo cell pharmacokinetics. Examples of various engineering techniques to improve (A) cell‐based gene therapy to extend duration of protein therapy, (B) targeting cells to local tissue via cell surface engineering 50, (C) pro‐drug cell therapy concentrates drug action within a microenvironment to minimize systemic exposure and decrease off‐target toxicities 45, and (D) engineered suicide switches as a safety control of cell therapy.
