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. 2019 May 8;8(9):935–944. doi: 10.1002/sctm.19-0023

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© 2019 The Authors. stem cells translational medicine published by Wiley Periodicals, Inc. on behalf of AlphaMed Press

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Time course of effects of mesenchymal stromal cell (MSC) coculture on glucose‐induced insulin secretion. Insulin secretion by mouse islets was measured at substimulatory (2 mM) and stimulatory (20 mM) glucose concentrations after coculture with maMSCs for 24, 48, or 72 hours, as shown by the key. Data are presented as mean + SEM, n = 10 observations in one experiment typical of three separate experiments using different islet preparations. ***, p < .001, versus non‐MSC‐treated islets controls at appropriate time points. Abbreviation: maMSCs, mouse adipose mesenchymal stromal cells.