Table 3.
Sex-adjusted Hazard ratios (HR) of stroke (ICD-10 I63) before the age of 50 years in individuals with different neighborhood SES at the age of 40 years.
Group | Individuals at risk | First events | Incidence rate per 10000 person-years |
Model A |
Model B |
Model C |
Model D |
||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
N | N | IR | 95% CI | HR | 95% CI | HR | 95% CI | HR | 95% CI | HR | 95% CI | ||||||
High | 227763 | 486 | 3.91 | 3.56 | 4.25 | 0.77 | 0.69 | 0.85 | 0.87 | 0.78 | 0.96 | 0.87 | 0.78 | 0.96 | 0.91 | 0.82 | 1.01 |
Middle | 741495 | 2000 | 4.99 | 4.77 | 5.21 | ref. | ref. | ref. | ref. | ||||||||
Low | 184193 | 665 | 6.46 | 5.96 | 6.95 | 1.25 | 1.14 | 1.37 | 1.19 | 1.08 | 1.30 | 1.16 | 1.06 | 1.27 | 1.12 | 1.02 | 1.23 |
HR: Hazard ratios; CI: Confidence interval. There was no significant interaction with sex, p=0.303.
Model A: adjusted for gender; Model B: adjusted for gender, marital status, educational level, immigrant status, and region of residence. Model C: adjusted for factors in Model B and neighbourhood goods and services (fast food restaurants, bars/pubs, physical activity facilities and health care resources). Model D: adjusted for factors in Model C and hospital diagnoses for hypertension, heart failure, and diabetes prior to the age of 40.