Table 6.
Overview of factors with strong evidence to be predictive of progression, overlap and differences between this review and the review of de Rooij et al., Wright et al., and Lievense et al.
| Prognostic factor | Teirlinck et al. factor predictive of | De Rooij et al. factor predictive of | Wright et al. factor predictive of | Lievense et al. factor predictive of |
|---|---|---|---|---|
| K-L grade at baseline | THR | Strong evidence for no association for clinical progression | Radiological progression or THR* | Not mentioned |
| Subchondral sclerosis at baseline | THR | Not mentioned | Radiological progression and/or THR | Not mentioned |
| Superior or (supero) lateral femoral head migration | THR | Not mentioned | Radiological progression and/or THR | Radiological progression and/or THR |
| Comorbidity | Clinical progression | Clinical progression (strong evidence for a course of function, weak evidence for a course of pain) | Not mentioned | Not mentioned |
| Low vitality | Quality of life in general: strong evidence of no association, specific for SF 36 vitality: strong evidence for clinical progression | Course of function | Not mentioned | Not mentioned |
| Age | Conflicted evidence for THR and radiological progression, moderate evidence for no association with clinical progression | Strong evidence for no association with pain and conflicted evidence for function | Radiological progression and/or THR | Conflicted evidence |
| Femoral osteophytes | Conflicted evidence | Not mentioned | Radiological progression and/or THR | Not mentioned |
| Hip pain at baseline | Conflicted evidence | Conflicted evidence | Radiological progression and THR | Not mentioned |
| JSW at baseline | Conflicted evidence | Not mentioned | Radiological progression and/or THR | Limited evidence for THR |
| Lequesne index score ≥ 10 at baseline | Conflicted evidence for THR, moderate evidence for radiological progression** | Conflicted evidence** | Radiological progression and/or THR | Not mentioned |
| Atrophic bone response | Conflicted evidence | Not mentioned | Conflicted evidence | Radiological progression |
*K-L grade 3 at baseline
**Function at baseline in general
bold text represents strong evidence to be predictive of progression