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. 2019 Aug 23;19:308. doi: 10.1186/s12884-019-2450-0

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Estimation of various biochemical and molecular measures at different time points. BDNF: Brain-derived neurotrophic factor; DNMT, DNA methyl transferase; HIF-1: Hypoxia-inducible factor-1; hsCRP: high sensitivity C-reactive protein; NGF: nerve growth factor; PEMT, phosphatidylethanolamine methyl transferase; PlGF: placental growth factor; PPAR gamma: peroxisome proliferator-activated receptor gamma; SAH, S-adenosylhomocysteine; SAM, S-adenosylmethionine; sEng: soluble endoglin; sFlt-1: soluble fms-like tyrosine kinase-1; Trkb: tyrosine receptor kinase B; VEGF: vascular endothelial growth factor