Fig. 3.

Down-regulation of CD36 inhibited miR-21 induced cell growth, migration and intracellular contents of lipids in human non-small cell lung cancer cells. a miR-21 mimic increased CD36 expression level. Cells were treated with miR-21 mimic or mimic control. The CD36 expression level was detected. b The protein expression level of CD36 was detected. c Cells were treated with shCD36 or control, The CD36 expression level was detected. d Cellular content of phospholipids was detected in human non-small cell lung cancer cells. e Cellular content of triglycerides was detected in human non-small cell lung cancer cells. f Cells were transfected with miR-21 mimic and/or shCD36. Cell number was counted after trypan blue staining. g Cells were treated with miR-21 and/or shCD36 for 24 h or 48 h. Migration abilities of cells were detected. *P < 0.05 VS control, **P < 0.01 VS control, ^##P < 0.01 VS miR-21 mimic