Table 3.

Mean monthly upper respiratory tract infection and acute otitis media rate in the study population, according to treatment group

Infection	Month
	1	2	3	4	5	6
URTI
Group A treatment 3 months (n = 100)
Mean	0.37	0.31*	0.28*	0.27*	0.31*	0.33
SD	0.37	0.36	0.46	0.31	0.49	0.61
Group B placebo (n = 109)
Mean	0.43	0.46	0.43	0.58	0.61	0.65
SD	0.49	0.58	0.52	0.46	0.61	0.55
Group C treatment 6 months (n = 37)
Mean	0.39	0.33*	0.31*	0.28*	0.30*	0.29
SD	0.25	0.30	0.22	0.24	0.19	0.28
AOM
Group A treatment 3 months (n = 100)
Mean	0.37	0.29*	0.27*	0.24*	0.26*	0.24*
SD	0.44	0.55	0.40	0.53	0.44	0.41
Group B placebo (n = 109)
Mean	0.46	0.52	0.49	0.56	0.66	0.78
SD	0.51	0.63	0.60	0.66	0.72	0.73
Group C treatment 6 months (n = 37)
Mean	0.35	0.31*	0.28*	0.26*	0.27*	0.25*
SD	0.31	0.28	0.30	0.31	0.25	0.33

AOM: acute otitis media; URTI: upper respiratory tract infection

* p < 0.05 vs placebo; no other significant differences between the groups