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Main neuroradiological findings over follow-up in 9 patients with HHH syndrome
| Pt | Age at MRI assessment (yrs) |
Brain atrophy | Spinal cord atrophy |
||
|---|---|---|---|---|---|
| Supratentorial | Corpus callosum | Subtentorial | |||
| 1 | 40 | + | – | + | n.d. |
| 2 | 27 | + | – | – | n.d. |
| 34 | ++ | + | – | n.d. | |
| 36 | ++ | + | + | ++ | |
| 3 | 19 | ++ | ++ | – | +++ |
| 4 | 18 | + | + | + | n.d. |
| 23 | + | + | + | + | |
| 5 | 25 | ++ | + | – | n.d. |
| 34 | ++ | ++ | + | – | |
| 6 | 28 | ++ | + | + | n.d |
| 7 | 12 | – | – | – | – |
| 8 | 8 | – | – | – | – |
| 9 | 8 | – | – | + | – |
Legend: +, mild; ++, moderate; +++, severe; absent, −. n.d not done
