Table 1.
Parameter* | Young male | Old male | Young female | Old female |
---|---|---|---|---|
Body weight (g) | 33.8 ± 2.8 | 35.1 ± 1.6 | 30.8 ± 1.9 | 37.3 ± 3.5 |
HW (mg) | 217.7 ± 12.9 | 264.2 ± 25.5 | 191.7 ± 16.4 | 189.2 ± 4.0a |
HW:BW (mg/g) | 6.6 ± 0.4 | 7.7 ± 0.9 | 6.4 ± 0.7 | 5.2 ± 0.4 |
TL (mm) | 18.6 ± 0.1 | 18.4 ± 0.4 | 18.7 ± 0.05 | 19.0 ± 0.2 |
HW:TL (mg/mm) | 11.7 ± 0.7 | 14.4 ± 1.3b | 10.2 ± 0.9 | 9.6 ± 0.2a |
Number of mice | 6 | 6 | 6 | 5 |
HW heart weight, BW body weight, TL tibia length
*Numbers represent mean ± SEM. Data were analyzed with two-way ANOVA with age and sex as main factors. Detailed statistical analysis is presented in Additional file 1: Table S1
aDenotes significant effect of sex (p < 0.05)
bDenotes significant effect of age (p < 0.05)