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. 2019 Aug 23;10:264. doi: 10.1186/s13287-019-1365-z

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Upper panels: Scanning electron microscopy of adipose tissue (AD)-derived mesenchymal stromal cells (MSCs). Note the presence of extracellular vesicles on AD-MSC surfaces. Lower panels: Representative graph of the intensity and hydrodynamic diameter of extracellular vesicle samples, analyzed using the dynamic light scattering technique. Graph shows two populations of extracellular vesicles obtained from nonpreconditioned (AD-MSC) and EPA-preconditioned MSCs (AD-MSC-EPA): one of lower intensity and medium size, characteristic of exosomes, and another with greater intensity and average size, characteristic of microvesicles. Green and blue lines denote the mean diameter