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. 2019 Aug 23;10:264. doi: 10.1186/s13287-019-1365-z

Fig. 7.

Fig. 7

Upper panels: Representative photomicrographs of lung parenchyma stained with hematoxylin-eosin. (a) in the C group, lung architecture presents normal alveoli (A) and airways (AW); (b) in the CLP-SAL group, lung damage was observed, with areas of alveolar collapse (asterisk) and alveolar septal inflammation (arrows); (c) administration of nonpreconditioned AD-MSCs (CLP-AD-MSC) attenuated alveolar collapse (asterisk) and alveolar septal inflammation (arrows); and (d) administration of EPA-preconditioned AD-MSCs (CLP-AD-MSC-EPA) led to a further reduction in alveolar collapse (asterisk) and alveolar septal inflammation (arrows). Lower panels: Cumulative diffuse alveolar damage (DAD) score representing injury from alveolar collapse, interstitial edema, and septal inflammation. Values are given as medians (interquartile ranges) of 8 animals in each group. *Significantly different from C group (P <0.05). #Significantly different from CLP-SAL group (P <0.05). ‡Significantly different from CLP-AD-MSC group (P <0.05)