FIG. 4.

Platelets and airway epithelial cells show increased mitochondrial and cellular oxidant production. (A, B) Mitochondrial superoxide production in (A) platelets and (B) airway epithelial cells as well as (C, D) total cellular H₂O₂ production measured in (C) platelets and (D) airway epithelial cells from healthy lean, asthmatic lean, healthy obese, and asthmatic obese individuals. All data are individual values of each subject with bars representing the mean and standard deviation. Statistical significance determined by one-way ANOVA. ^#p < 0.05 and *p < 0.01 versus respective healthy control if not otherwise noted. n = 10 for platelets and n = 5 for airway epithelial cells. H₂O₂, hydrogen peroxide.