Table I.
Analysis of allelic and genotypic frequencies of the MTHFR 677C>T polymorphism between individuals with normal weight, overweight/obese, overweight, and obese.
| Genotype/allele | NW BMI <25 n=172 |
Overweight /obesity BMI ≥25 n= 144 |
OR (95% CI) | *p value |
|---|---|---|---|---|
| C/ C | 43 | 34 | Reference | |
| C/T | 90 | 84 | 1.18 (0.69–2.02) | 0.55 |
| T/T | 39 | 26 | 0.84 (0.43–1.65) | 0.62 |
| C | 176 | 152 | Reference | |
| T | 168 | 136 | 0.94 (0.69–1.28) | 0.69 |
| NW BMI<25 n=172 |
Overweight (≥25BMI <30) n=74 |
|||
| C/C | 43 | 16 | Reference | |
| C/T | 90 | 49 | 1.46 (0.75–2.9) | 0.27 |
| T/T | 39 | 9 | 0.62 (0.25–1.6) | 0.31 |
| C | 176 | 81 | Reference | |
| T | 168 | 67 | 0.87 (0.59–1.3) | 0.47 |
| NW BMI <25 n=172 |
Obesity BMI >30 n=70 |
|||
| C/C | 43 | 18 | Reference | |
| C/T | 90 | 36 | 0.96 (0.49–1.87) | 0.89 |
| T/T | 39 | 16 | 0.98 (0.44–2.18) | 0.96 |
| C | 176 | 72 | Reference | |
| T | 168 | 68 | 0.99 (0.67–1.47) | 0.96 |
*Chi square test.