Table II.
Analysis of allelic and genotypic frequencies of the MTHFR 677C>T polymorphism between males with BMI <25 vs BMI ≥25 and females with waist circumference <88 cm vs ≥88 cm.
| Genotype/allele | Male BMI <25 n=37 |
Male BMI ≥25 n= 47 |
OR (95% CI) | *p value |
|---|---|---|---|---|
| C/ C | 7 | 18 | Reference | |
| C/ T | 21 | 23 | 0.43 (0.15–1.22) | 0.10 |
| T/ T | 9 | 6 | 0.26 (0.07–1.00) | <0.05 |
| C | 35 | 59 | Reference | |
| T | 39 | 35 | 0.53 (0.29–0.99) | <0.05 |
| Genotype/allele | Female <88 cm n=155 |
Female ≥88 cm n=77 |
OR (95% CI) | *p value |
| C/ C | 36 | 43 | Reference | |
| C/ T | 79 | 22 | 0.23 (0.12–0.45) | <0.001 |
| T/ T | 40 | 12 | 0.25 (0.12–0.55) | <0.001 |
| C | 151 | 108 | Reference | |
| T | 159 | 46 | 0.40 (0.27–0.61) | <0.001 |