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. 2019 Jan 22;38(4):461–467. doi: 10.2478/jomb-2018-0046

Table III.

Analysis of allelic and genotypic frequencies of the MTHFR 677C>T polymorphism between overweight/obese individuals depending on the level of triglycerides, cholesterol, and glucose.

Genotype/alleles Overweight /obesity
triglycerides ≤1.71 mmol/L
n=109
Overweight /obesity
triglycerides >1.71 mmol/L
n=35
OR (95% CI) *p value
C/C 25 12 Reference
C/T 60 21 0.73 (0.31–1.70) 0.47
T/T 24 2 0.17 (0.04–0.86) 0.02
C 110 45 Reference
T 108 25 0.57 (0.32–0.99) 0.04
Overweight /obesity
cholesterol ≤5.2 mmol/L
n=126
Overweight /obesity
cholesterol >5.2 mmol/L
n=18
C/C 30 6 Reference
C/T 70 12 0.86 (0.29–2.50) 0.78
T/T 26 0 0.09 (0.01–1.65) 0.02
C 130 24 Reference
T 122 12 0.53 (0.26–1.11) 0.09
Overweight /obesity glucose
≤5.55 mmol/L
n=111
Overweight /obesity glucose
>5.55 mmol/L
n=33
C/C 28 9 Reference
C/T 65 18 0.86 (0.35–2.15) 0.75
T/T 18 6 1.04 (0.32–3.41) 0.95
C 121 36 Reference
T 101 30 0.99 (0.58–1.73) 0.99

*Chi square test.