Shrew HBV infection patterns. (A) Mean CSHBV concentrations in solid organs (grams) and blood (milliliters), SDs. (B) In situ hybridization of CSHBV. (C) Shrew serum reacting with CSHBV proteins. Red, antibody binding; blue, nuclei. (D and E) Major sampling sites in Germany, Sierra Leone, and Ivory Coast; neighbor-joining phylogenies. Trees encompass 773 (CSHBV) and 1,432 (MSHBV) nucleotides. One CSHBV strain for which only a smaller fragment was characterized is not shown.