Table 1.

Correlation between antibiotic consumption that decreased remarkably and the corresponding antibiotic susceptibility

Pathogens	Antibiotics	Trend for susceptibility			Correlation analysis
		r	p	Trend	Antibiotic in consumption	r	p	Correlation
Klebsiella pneumoniae	Cefazolin	−0.457	0.362	Stable	1GCs	0.404	0.427	No correlation
	Cefepime	0.744	0.014	Increasing	4GCs	−0.763	0.010	Negative
	Ciprofloxacin	0.833	0.003	Increasing	Fluoroquinolones	−0.849	0.002	Negative
Amikacin	0.607	0.063	Stable	Glycopeptides	−0.627	0.052	No correlation
Escherichia coli	Cefazolin	−0.097	0.855	Stable	1GCs	−0.335	0.516	No correlation
	Cefepime	0.963	0.000	Increasing	4GCs	−0.763	0.010	Negative
	Ciprofloxacin	0.953	0.000	Increasing	Fluoroquinolones	−0.857	0.002	Negative
Amikacin	0.918	0.000	Increasing	Glycopeptides	−0.784	0.007	Negative
Acinetobacter baumannii	Cefepime	−0.110	0.762	Stable	4GCs	0.156	0.667	No correlation
	Ciprofloxacin	0.713	0.031	Increasing	Fluoroquinolones	−0.772	0.015	Negative
Amikacin	0.749	0.013	Increasing	Glycopeptides	−0.871	0.001	Negative
Pseudomonas aeruginosa	Cefepime	−0.110	0.762	Stable	4GCs	0.219	0.543	No correlation
	Ciprofloxacin	0.800	0.005	Increasing	Fluoroquinolones	−0.647	0.043	Negative
Amikacin	0.895	0.000	Increasing	Glycopeptides	−0.861	0.001	Negative
Staphylococcus aureus	Ciprofloxacin	0.915	0.000	Increasing	Fluoroquinolones	−0.867	0.001	Negative
Gentamicin	0.902	<0.001	Increasing	Glycopeptides	−0.818	0.004	Negative
Coagulase- negative staphylococcus	Ciprofloxacin	0.800	0.005	Increasing	Fluoroquinolones	−0.686	0.028	Negative
Gentamicin	0.968	<0.001	Increasing	Glycopeptides	−0.886	<0.001	Negative
Enterococcus faecium	Ciprofloxacin	0.394	0.260	Stable	Fluoroquinolones	−0.598	0.068	No correlation
Gentamicina	0.921	<0.001	Increasing	Glycopeptides	−0.827	0.003	Negative
Enterococcus faecalis	Ciprofloxacin	0.940	<0.001	Increasing	Fluoroquinolones	−0.968	<0.001	Negative
Gentamicina	0.898	<0.001	Increasing	Glycopeptides	−0.800	0.005	Negative

Note: ^aGentamicin with a high concentration.

Abbreviations: 1GCs, first-generation cephalosporins; 4GCs, fourth-generation cephalosporins.