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. 2019 Aug 20;15:1019–1027. doi: 10.2147/TCRM.S210872

Table 2.

Correlation between antibiotic consumption that increased remarkably and the corresponding antibiotic susceptibility

Pathogens Antibiotics Trend for susceptibility Correlation analysis
r p Trend Antibiotic in consumption r p Correlation
Escherichia coli Imipenem 0.073 0.840 Stable Carbapenems −0.216 0.549 No correlation
SCF −0.530 0.115 Stable 3GCs/β-lactamase inhibitorsa −0.639 0.064 No correlation
Ceftazidime 0.665 0.051 Stable 3GC sensitive to paeb 0.488 0.182 No correlation
Klebsiella pneumoniae Imipenem −0.642 0.046 Decreasing Carbapenems −0.649 0.042 Negative
SCF −0.740 0.014 Decreasing 3GCs/β-lactamase inhibitorsa −0.708 0.033 Negative
Ceftazidime 0.347 0.360 Stable 3GC sensitive to paeb 0.511 0.160 No correlation
Acinetobacter baumannii Imipenem −0.056 0.878 Stable Carbapenems 0.077 0.832 No correlation
SCF −0.783 0.007 Decreasing 3GCs/β-lactamase inhibitorsa −0.775 0.014 Negative
Ceftazidime −0.267 0.488 Stable 3GC sensitive to paeb −0.322 0.398 No correlation
Pseudomonas aeruginosa Imipenem 0.167 0.644 Stable Carbapenems −0.045 0.901 No correlation
SCF 0.387 0.269 Stable 3GCs/β-lactamase inhibitorsa −0.064 0.870 No correlation
Ceftazidime −0.488 0.152 Stable 3GC sensitive to paeb −0.477 0.163 No correlation
Staphylococcus aureus Linezolid 0.410 0.274 Stable Linezolid 0.228 0.555 No correlation
Vancomycin Maintained 100% Glycopeptides ／ ／ No correlation
Coagulase-negative staphylococcus Linezolid −0.275 0.473 Stable Linezolid −0.281 0.464 No correlation
Vancomycin Maintained 100% Glycopeptides ／ ／ No correlation
Enterococcus faecium Linezolid −0.320 0.401 Stable Linezolid 0.098 0.802 No correlation
Vancomycin 0.925 <0.001 Increasing Glycopeptides 0.633 0.049 Positive
Enterococcus faecalis Linezolid 0.483 0.188 Stable Linezolid 0.122 0.754 No correlation
Vancomycin 0.735 0.015 Increasing Glycopeptides 0.752 0.012 Positive

Note: aSince the consumption of 3GCs/β-lactamase inhibitors increased remarkably among 3GCs and SCF belongs to 3GCs/β-lactamase inhibitors, the correlation was conducted between the corresponding susceptibility and consumption. bSince the consumption of 3GCs sensitive to pae increased remarkably among 3GCs and ceftazidime belongs to this antibiotic type, the correlation was conducted between the corresponding susceptibility and consumption.

Abbreviations: 3GCs, third-generation cephalosporins; pae, P. aerugino; SCF, cefoperazone/sulbactam.