Table 3.
Correlation between isolations of important pathogens (ESBL-producing Enterobacteriaceae and MRSA) and antibiotic consumption
| Pathogens | Trend for susceptibility | Correlation analysis | ||||||
|---|---|---|---|---|---|---|---|---|
| r | p | Trend | Antibiotic in consumption | r | p | Correlation | ||
| Escherichia coli | ESBL | −0.745 | 0.013 | Decreasing | 3GCs | 0.270 | 0.452 | No correlation |
| PCs with extended spectrum | 0.430 | 0.215 | No correlation | |||||
| Carbapenems | −0.877 | 0.001 | Negative | |||||
| Cephalosporins/β-lactamase inhibitors | −0.730 | 0.017 | Negative | |||||
| Fluoroquinolones | 0.545 | 0.104 | No correlation | |||||
| Klebsiella pneumoniae | ESBL | −0.789 | 0.007 | Decreasing | 3GCs | −0.134 | 0.712 | No correlation |
| PCs with extended spectrum | −0.576 | 0.081 | No correlation | |||||
| Carbapenems | 0.136 | 0.708 | No correlation | |||||
| Cephalosporins/β-lactamase inhibitors | −0.521 | 0.123 | No correlation | |||||
| Fluoroquinolones | 0.865 | 0.001 | Positive | |||||
| Staphylococcus aureus | MRSA | −0.767 | 0.009 | Decreasing | Penicillins | 0.615 | 0.059 | No correlation |
| Cephalosporins | 0.198 | 0.584 | No correlation | |||||
| β-lactamase antibiotics | 0.233 | 0.518 | No correlation | |||||
| Carbapenems | −0.524 | 0.120 | No correlation | |||||
| Fluoroquinolones | 0.781 | 0.008 | Positive | |||||
| Glycopeptides | −0.142 | 0.695 | No correlation | |||||
Abbreviations: 3GCs, third-generation cephalosporins; PCs, penicillins; ESBL, extended-spectrum β-lactamase; MRSA, methicillin-resistant Staphylococcus aureus.