Table 2.
Rate per 1000a (and frequency) of obstetric and neonatal outcomes for singleton pregnancies from the Consortium of Safe Labor 2002–2008 (n = 205521).
| Women without autoimmune disease (n = 204384) | Autoimmune Disease |
|||||
|---|---|---|---|---|---|---|
| Type I Diabetes (n = 507) | Systemic Lupus Erythematosus (n = 202) | Crohn’s Disease (n = 169) | Multiple Sclerosis (n = 146) | Rheumatoid Arthritis (n = 123) | ||
| Cesarean Delivery | 278.5 (56926) | 670.6 (340)b | 391.1 (79)b | 360.9 (61)b | 424.7 (62)b | 390.2 (48)b |
| Prelabor cesarean | 113.6 (23218) | 270.2 (137)b | 183.2 (37)b | 183.4 (31)b | 232.9 (34)b | 211.4 (26)b |
| After spontaneous labor | 93.0 (19016) | 195.3 (99)b | 123.8 (25) | 118.3 (20) | 123.3 (18) | 130.1 (16) |
| After induced labor | 71.9 (14692) | 205.1 (104)b | 84.2 (17) | 59.2 (10) | 68.5 (10) | 48.8 (6) |
| Preterm Birth | 111.0 (22701) | 426.0 (216)b | 376.2 (76)b | 195.3 (33)b | 191.7 (28)b | 178.8 (22)b |
| Spontaneous | 78.4 (16038) | 248.5 (126)b | 232.7 (47)b | 130.1 (22)b | 143.8 (21)b | 154.4 (19)b |
| Indicated | 17.8 (3650) | 145.9 (74)b | 103.9 (21)b | 29.5 (5)b | 27.3 (4) | 16.2 (2) |
| Preeclampsia | 46.4 (9498) | 159.7 (81)b | 138.6 (28)b | 82.8 (14)b | 61.6 (9) | 81.3 (10) |
| NICU Admission | 115.4 (23593) | 408.2 (207)b | 282.1 (57)b | 195.3 (33)b | 164.3 (24) | 195.1 (24)b |
| Neonatal Respiratory Distress Syndrome | 31.1 (6357) | 130.1 (66)b | 113.8 (23)b | 47.3 (8) | 34.0 (5) | 48.7 (6) |
| Small for Gestational Age | 109.3 (22350) | 65.0 (33)b | 178.2 (36)b | 124.2 (21) | 75.3 (11) | 170.7 (21)b |
| Perinatal Mortality | 5.9 (1214) | 13.8 (7)b | 19.8 (4)b | 5.9 (1) | 0 (0) | 0 (0) |
a
Rates per 1000 are specific for each autoimmune disease category (rate = (outcome n/autoimmune disease N)*1000).
b
p < 0.05 indicates rates among women with autoimmune disease different than rates among women without autoimmune disease. P-values obtain using generalized estimating equations to account for women who had more than one pregnancy in the study.