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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: J Autoimmun. 2019 Jun 24;103:102291. doi: 10.1016/j.jaut.2019.06.002

Figure 5:

Figure 5:

Type I IFNs suppress TReg activation and functionality following UVB exposure. (A and B) Ten-week-old iNZM mice were treated with 100mJ/cm2 on their dorsum for 5 days and dLNs were analyzed via flow cytometry 24hrs or 2 weeks post treatment. Each dot represents an individual mouse. (A) Changes in T regulatory cells: CD3+CD4+CD25+FoxP3+. (B) T regulatory cell activation: CD69+. (C) Percent proliferation of CD4+ cells in TReg suppression assay. n=three independent experiments in duplicate. ANOVA testing was used to determine significance.