Results for hippocampal GFAP reactivity proportional area at PID 3 and PID 7 are shown graphically on the left. REGCCI and DHACCI are shown in solid black and white bars, respectively, while corresponding SHAM groups are shown as spotted gray and latticed white for SHAMREG and SHAMDHA rats. CCI significantly decreased GFAP reactivity in the hippocampus at PID 7 relative to SHAM controls (&p=0.03 main effect of CCI, adjusted p value 0.001). There was a trend toward a treatment by time interaction in the hippocampus (p=0.06) with GFAP immunoreactivity in DHACCI hippocampus returning toward SHAM levels by PID 7. On the right, representative images of hippocampal GFAP reactivity are shown for SHAMREG, REGCCI and DHACCI. The scale bar is 100 microns. DHACCI GFAP did not differ from sham at either time point.