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R-47 does not interfere with paclitaxel-induced apoptosis of NSCLC cells. Cells were treated with R-47, paclitaxel, or the combination for 48 hours. Quantification of apoptotic cells was determined by the Annexin V/PI assay. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 vs control; n.s., not significant (P > 0.05). Data are expressed as the mean ± SEM of three independent experiments. Pac, paclitaxel.
