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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: Ocul Surf. 2019 Apr 22;17(3):491–501. doi: 10.1016/j.jtos.2019.04.003

Table 1.

Inter-reader and grade-regrade agreement in evaluating meibomian gland variants and dropout areas.

Intraclass correlation coefficient (95% confidence interval)
Meibomian Gland Feature Inter-reader agreement (N=897) Grade-regrade agreement (N=34)
Total number 0.89 (0.88, 0.91) 0.80 (0.65, 0.90)
Distorted 0.71 (0.67, 0.74) 0.59 (0.35, 0.78)
Tortuous 0.43 (0.37, 0.49) 0.88 (0.79, 0.94)
Hooked 0.61 (0.57, 0.66) 0.77 (0.62, 0.89)
Short 0.61 (0.56, 0.65) 0.54 (0.28, 0.75)
Thick 0.32 (0.25, 0.38) 0.23 (−0.08, 0.55)
Thin 0.22 (0.15, 0.29) 0.25 (−0.06, 0.56)
Overlap 0.64 (0.60, 0.68) 0.24 (−0.07, 0.55)
Ghost 0.56 (0.51, 0.60) 0.78 (0.63, 0.89)
Dropout 0.40 (0.34, 0.46) 0.26 (−0.05, 0.57)
Area Measurements*
Total area 0.91 (0.90, 0.92) 0.98 (0.96, 0.99)
Total dropout area including fluffy areas and ghost glands as dropped out. 0.65 (0.61, 0.69) 0.70 (0.50, 0.84)
Percent dropout area including fluffy areas and ghost glands as dropped out. 0.52 (0.47, 0.57) 0.74 (0.56, 0.87)
Total dropout area excluding fluffy areas and ghost glands as dropped out. 0.56 (0.51, 0.61) 0.39 (0.10, 0.66)
Percent dropout area excluding fluffy areas and ghost glands as dropped out 0.52 (0.47, 0.57) 0.57 (0.32, 0.77)
*

Number of missing values for inter-reader agreement: 4 for total area, 3 for total dropout area (both for including and excluding fluffy areas and ghost glands), 6 for percent dropout area (both for including and excluding fluffy areas and ghost glands)