Table 4:

Clinically assessed meibomian gland secretions from the central 5 meibomian glands of the lower lid and the meibomian gland morphological features in the middle 1/3 of the lower lid assessed in the reading center

Features in the lower lid middle third		Clear secretion (n=82)	Mild haze/cloudiness (n=145)	Paste like secretion (n=71	No Secretion (N=170)	p-value
Total number	Mean (SD)	7.32 (1.66)	7.08 (2.06)	7.32 (1.50)	7.17 (1.97)	0.76
Distorted	Mean (SD)	1.51 (1.47)	1.50 (1.51)	1.65 (1.44)	1.66 (1.44)	0.80
Tortuous	Mean (SD)	0.10 (0.41)	0.07 (0.31)	0.06 (0.32)	0.04 (0.24)	0.48
Hooked	Mean (SD)	0.07 (0.35)	0.04 (0.25)	0.03 (0.17)	0.06 (0.27)	0.50
Short	Mean (SD)	2.10 (1.79)	1.39 (1.60)	1.52 (1.67)	1.73 (1.94)	0.02
Thick	Mean (SD)	0.04 (0.27)	0.04 (0.23)	0.01 (0.12)	0.02 (0.17)	0.59
Thin	Mean (SD)	0.13 (0.44)	0.06 (0.26)	0.03 (0.17)	0.06 (0.27)	0.25
Overlap	Mean (SD)	0.11 (0.31)	0.08 (0.28)	0.03 (0.17)	0.04 (0.21)	0.09
Ghost	Mean (SD)	0.31 (0.82)	0.36 (1.14)	0.83 (1.72)	0.65 (1.47)	0.046
Dropout	Mean (SD)	0.16 (0.69)	0.17 (0.47)	0.23 (0.61)	0.16 (0.48)	0.87
Tadpoling	No	82 (18%)	143 (31%)	70 (15%)	168 (36%)	0.77
	Yes	0 (0%)	2 (40%)	1 (20%)	2 (40%)
Gaps	No	82 (18%)	145 (31%)	70 (15%)	169 (36%)	0.44
	Yes	0 (0%)	0 (0%)	1 (50%)	1 (50%)
No Lid margin extension of meibomian glands	No	78 (18%)	138 (31%)	65 (15%)	161 (36%)	0.67
	Yes	4 (15%)	7 (27%)	6 (23%)	9 (35%)
Fluffy areas	No	77 (18%)	135 (31%)	67 (15%)	161 (37%)	0.95
	Yes	5 (18%)	10 (36%)	4 (14%)	9 (32%)
	Total	82 (18%)	145 (31%)	71 (15%)	170 (36%)
Meibomian gland feature composite score	Mean (SD)	22.18 (16.90)	16.96 (17.31)	22.00 (19.25)	21.46 (20.65)	0.10
% dropout including ghost glands and fluffy areas*	Mean (SD)	0.28 (0.15)	0.31 (0.18)	0.36 (0.20)	0.33 (0.22)	0.08
% dropout excluding ghost glands and fluffy areas*	Mean (SD)	0.16 (0.11)	0.18 (0.12)	0.21 (0.12)	0.21 (0.17)	0.06

^*3 lids with mild haze/cloudiness and 1 eye with paste have missing dropout area