Correlation matrices were used to determine Inter-correlations of COX activity within certain regions (i.e. within subregions of the hippocampus or the amygdala) as well between regions. The color and size of each tile reflects the direction and strength of the correlation respectively, as indicated by the color bar on the right. The asterisk indicates a statistically significant correlation (P<0.05). Separate correlation matrices are shown for HR (left) and LR (right). The color of squares at each convergence of a row and column indicates the level of correlation according to the color bar on the right. Inter-correlations within the amygdala were positive, particularly in LR animals. Within the hippocampus, there were positive interregional correlations, although the effect was more prominent in HRs. HR/LR rats exhibited distinct cross-regional correlations (i.e. between hippocampus and the prefrontal cortex or dorsal raphe). Abbreviations: lateral amygdala (LA); basolateral amygdala (BLA); basomedial amygdala (BMA); central amygdala (CeA); DG, dentate gyrus; CA, cornu ammonis; dorsal raphe (DR); Prl, prelimbic cortex.