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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Exp Neurol. 2019 May 28;320:112967. doi: 10.1016/j.expneurol.2019.112967

Table 1.

Significantly altered TLR2/4 related gene expression in human sural nerves.

Gene ID Gene Symbol Gene Description ChipInspector + GenePattern
208 AKT2 v-akt murine thymoma viral oncogene homolog 2 −1.12
841 CASP8 caspase 8, apoptosis-related cysteine peptidase −1.08
942 CD86 CD86 molecule 1.21
6373 CXCL11 chemokine (C-X-C motif) ligand 11 −1.17
4283 CXCL9 chemokine (C-X-C motif) ligand 9 −1.33
2353 FOS FBJ murine osteosarcoma viral oncogene homolog 1.46
3454 IFNAR1 interferon (alpha, beta and omega) receptor 1 1.15
3455 IFNAR2 interferon (alpha, beta and omega) receptor 2 −1.1
3663 IRF5 interferon regulatory factor 5 −1.14
3725 JUN jun proto-oncogene 1.16 1.14
3929 LBP lipopolysaccharide binding protein −1.31 −1.59
5604 MAP2K1 mitogen-activated protein kinase kinase 1 −1.14
5609 MAP2K7 mitogen-activated protein kinase kinase 7 1.12
6885 MAP3K7 mitogen-activated protein kinase kinase kinase 7 −1.09
1326 MAP3K8 mitogen-activated protein kinase kinase kinase 8 −1.16
5594 MAPK1 mitogen-activated protein kinase 1 1.15
5602 MAPK10 mitogen-activated protein kinase 10 −1.13
1432 MAPK14 mitogen-activated protein kinase 14 −1.12
5599 MAPK8 mitogen-activated protein kinase 8 −1.08
5291 PIK3CB phosphoinositide-3-kinase, catalytic, beta polypeptide −1.14 −1.4
5294 PIK3CG phosphoinositide-3-kinase, catalytic, gamma polypeptide −1.1
5295 PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.18
5296 PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 1.09
8503 PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) −1.12
6772 STAT1 signal transducer and activator of transcription 1, 91kDa −1.14
23118 TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 1.11
148022 TICAM1 toll-like receptor adaptor molecule 1 1.16 1.16

Previously published data (Hur et al., 2011) represented as relative fold changes in sural nerve gene expression between neuropathy patients who either worsened in their neuropathy (progressors) or had no change in neuropathy (non-progressors), with non-progressors used as the reference set for the two different analyses (ChipInspector and ChipInspector + GenePattern).