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MCT1+/− retina has normal structure but reduced levels of MCT1. (a) Frozen section of 14-month-old MCT1+/− retina. Retinal structure is normal, and while the abundance of MCT1 is decreased relative to age-matched WT littermates, the distribution of MCT1 is not changed. (b) Immunoblot analysis of RPE and retinal lysates demonstrates greater than 50% reduction in MCT1 levels in MCT1+/− as compared to WT mice
