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. Author manuscript; available in PMC: 2019 Aug 25.
Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2007 Jun 5;144B(4):417–423. doi: 10.1002/ajmg.b.30340

Table 3.

Gene-Lifecourse interaction for alcohol use in adolescence and young adulthood: regression estimates using five monoamine genes

No genes 5HTT DAT1 DRD4 DRD2 MAOA (male) MAOA (female) All genes
Predictors β p β p β p β p β p β p β P β p
Intercept 1.087 0.0001 1.129 0.0001 1.125 0.0001 1.081 0.0001 1.051 0.0001 1.277 0.0001 1.082 0.0001 1.125 0.0001
Age ≥19 1.095 0.0001 0.999 0.0001 1.017 0.0001 1.086 0.0001 1.663 0.0001 1.455 0.0001 0.859 0.0001 0.985 0.0001
Male 0.319 0.0001 0.320 0.0001 0.321 0.0001 0.319 0.0001 0.320 0.0001 0.322 0.0001
Black −0.522 0.0001 −0.527 0.0001 −0.525 0.0001 −0.514 0.0001 −0.53 0.0001 −0.588 0.0018 −0.183 0.028 −0.520 0.0002
Hispanic −0.251 0.0019 −0.25 0.002 −0.253 0.0017 −0.242 0.0026 −0.259 0.0016 −0.245 0.0612 −0.232 0.131 −0.259 0.0017
Asian −0.657 0.0001 −0.654 0.0001 −0.663 0.0001 −0.646 0.0001 −0.668 0.0001 −0.609 0.0057 −0.742 0.027 −0.660 0.0001
Any S −0.063 0.2215 −0.062 0.22
Any S * Age≥19 0.144 0.0145 0.145 0.013
Any 9R −0.099 0.0464 −0.098 0.047
Any 9R * Age≥19 0.206 0.0003 0.198 0.0006
Any 3R 0.063 0.642 0.066 0.62
Any 3R * Age≥19 0.470 0.003 0.456 0.0040
7R/7R −0.106 0.470 −0.107 0.46
7R/7R * Age≥19 0.461 0.007 0.466 0.0068
Any A1 0.086 0.082 0.084 0.091
Any A1 * Age≥19 −0.156 0.005 −0.151 0.0069
Any 3R 0.114 0.128 0.114 0.079
Any 3R * Age≥19 −0.255 0.0039 0.0383 0.596
−2 Log likelihood 30173 30167 30160 30159 30165 14652 15314 30131
N of persons 2466 2466 2466 2466 2466 1169 1297 2466
N of observations 8739 8739 8739 8739 8739 4098 4641 8739