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. Author manuscript; available in PMC: 2019 Aug 25.
Published in final edited form as: Bioconjug Chem. 2017 Jun 30;28(8):2114–2124. doi: 10.1021/acs.bioconjchem.7b00296

Figure 1.

Figure 1.

Attachment of proteins to the P22 VLP via sortase. Construction of the P22 VLP containing a C-terminal LPETG amino acid sequence is predicted to allow modular attachment of N-terminal polyglycine (polyG; red circles) containing proteins (purple) via sortase catalyzed peptide bond formation between the N-terminal glycine of the polyG-protein and C-terminal threonine of the P22 coat proteins.