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. 2019 Jul 1;10(7):e00058. doi: 10.14309/ctg.0000000000000058

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© 2019 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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Figure 2. — Immune checkpoint distribution on lymphocyte subsets in advanced HCC at the baseline. (a) The percentage of immune checkpoint-positive cells among NK, CD3⁺CD56⁺ cells (NKT and CD3^brightCD56⁺ T cells), and T cells in the blood (n = 21), tumor tissue (n = 16), and nontumoral tissue (n = 13). (b) The percentage of immune checkpoint-positive cells among CD4⁺ or CD8⁺ T cells in the blood (n = 21), tumor tissue (n = 16), and nontumoral tissue (n = 13). Each dot represents a patient. The nonparametric Kruskal-Wallis one-way analysis of variance was used for multiple comparisons. HCC, hepatocellular carcinoma.