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Immunohistochemical staining of ZO-1 from normal control group (A), colitis model group (B), Sb treatment group (C), mesalazine treatment group (D), and combination treatment group (E) (Original magnification ×400). The mean ZO-1 score from group A to group E (F). ∗P < 0.01, †P < 0.05. Sb: Saccharomyces boulardii; ZO-1: Zona occludens.
