Table 3.
Baseline | 6 months | 12 months | Between Group Comparison by GEE |
||||
---|---|---|---|---|---|---|---|
P (T*G) |
P (Time) |
P (Group) |
|||||
Arterial Function | |||||||
bSBP (mmHg) | CON | 140.6±26.6 | 130.5±29.4 | 138.1±27.5 | 0.21 | 0.92 | 0.01 |
PRO | 144.6±23.1 | 149.2±21.6θ | 148.9±23.3 | ||||
PRO+EX | 132.3±21.3‡ | 136.4±30.4‡ | 132.4±27.9‡ | ||||
bDBP (mmHg) | CON | 81.4±15.2 | 74.2±13.8* | 74.9±15.2** | 0.22 | 0.16 | 0.88 |
PRO | 78.2±13.4 | 78.8±15.1 | 78.5±12.5 | ||||
PRO+EX | 77.6±13.5 | 77.8±14.4 | 76.6±16.6 | ||||
aSBP (mmHg) | CON | 129.5±13.5 | 118.4±28.2 | 121.8±21.7 | 0.14 | 0.76 | 0.03 |
PRO | 130.1±23.9 | 136.0±21.2 | 134.3±22.3 | ||||
PRO+EX | 123.2±21.3 | 126.3±23.9 | 118.0±25.9 | ||||
aDBP (mmHg) | CON | 83.5±14.1 | 76.3±14.7* | 75.1±13.8** | 0.29 | 0.10 | 0.73 |
PRO | 81.7±23.1 | 80.4±15.7 | 79.0±12.1 | ||||
PRO+EX | 78.5±13.1 | 79.5±14.1 | 76.3±18.0 | ||||
Aix75 (%) | CON | 24.7±11.7 | 19.7±14.4 | 22.7±10.6 | 0.58 | 0.24 | 0.43 |
PRO | 25.6±10.9 | 25.6±11.4 | 25.7±11.0 | ||||
PRO+EX | 25.0±13.1 | 21.3±2.7 | 21.8±14.4 | ||||
PWV (m/s) | CON | 9.4±2.6 | 8.7±2.3* | 10.1±4.0 | 0.08 | 0.30 | 0.16 |
PRO | 10.8±3.5 | 10.3±2.8 | 9.6±2.7 | ||||
PRO+EX | 9.3±3.1 | 9.9±4.0 | 8.7±2.2 |
bSBP: brachial systolic blood pressure, bDBP: brachial diastolic blood pressure, aSBP: aortic systolic blood pressure, aDBP: aortic diastolic blood pressure, Aix 75: augmentation index at heart rate 75 beats per minute, PWV: pulse wave velocity
: indicates significant within-group difference between baseline vs 6 months in outcome measures by paired t-test
: indicates significant within-group difference between baseline vs 12 months in outcome measures by paired t-test
: indicates a significant group difference compared to CON group by LSD post-hoc analysis at a time point
: indicates a significant group difference compared to PRO group by LSD post-hoc analysis at a time point