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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: J Invest Dermatol. 2019 Mar 21;139(9):1985–1992.e10. doi: 10.1016/j.jid.2019.01.036

Figure 3. Effects of ABCB5 mutations on proliferation of melanoma cells.

Figure 3.

(a) Proliferation rates of 17T clones were assayed over 3 days. All 17T clones overexpressing ABCB5 mutants had a significant increase of their proliferation rate compared with the ABCB5 WT-overexpressing clone for each time point. (b) Proliferation rates of 63T ABCB5 clones were measured 3 and 4 days after seeding. The proliferation rate of the S1184P mutant was found to be very highly statistically significant only when compared with the parental WT 63T cells. *P < 0.05, **P < 0.01, ***P <0.001,****P < 0.0001. n = 4. Values are the mean ± standard error of the mean. WT, wild type.