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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: J Steroid Biochem Mol Biol. 2019 May 28;192:105383. doi: 10.1016/j.jsbmb.2019.105383

TABLE 1:

Photolabeling efficiencies of KK200 in ELIC-α1GABAAR.

ELIC-α1GABAAR Intact protein MS Middle-down MS
TM3 TM4
WT 11.3 8.0 1.8
Q242L 11.8 6.1 1.9
Q242W 11.7 5.2 1.7
W246L 11.5 3.7 1.2

Labeling efficiencies of KK200 (%) in intact protein MS and middle-down MS analyses for the ELIC-α1GABAAR WT and the mutated receptors.