Table 1.
Population characteristics of persons diagnosed with multiple myeloma in the Puerto Rico Central Cancer Registry and the United States Surveillance, Epidemiology, and End Results Program (SEER) 1987–2013
| Characteristics | Overall US SEER | Non-Hispanics US SEER |
Hispanics US SEER | Puerto Rico4 | ||||
|---|---|---|---|---|---|---|---|---|
| (n=67,733) | (n=61,138) | (n=6,595) | (n=3,018) | |||||
| n | % | n | % | n | % | n | % | |
| Male | 36,177 | 53.4 | 32,691 | 53.5 | 3,486 | 52.9 | 1,537 | 50.9 |
| Median age at diagnosis, years | 69 | 69 | 65 | 69 | ||||
| Age at diagnosis in years | ||||||||
| 40-59 | 17,410 | 25.7 | 15,190 | 24.9 | 2,220 | 33.7 | 686 | 22.7 |
| 60-69 | 18,401 | 27.2 | 16,503 | 27.0 | 1,898 | 28.8 | 889 | 29.5 |
| 70-79 | 19,460 | 28.7 | 17,812 | 29.1 | 1,648 | 25.0 | 947 | 31.4 |
| ≥80 | 12,462 | 18.4 | 11,633 | 19.0 | 829 | 12.6 | 496 | 16.4 |
| Year of diagnosis | ||||||||
| 1987–1997 | 13,226 | 19.5 | 12,375 | 20.2 | 851 | 12.9 | 999 | 33.1 |
| 1998-2002 | 12,670 | 18.7 | 11,500 | 18.8 | 1,170 | 17.7 | 388 | 12.8 |
| 2003-2007 | 17,227 | 25.4 | 15,446 | 25.3 | 1,781 | 27.0 | 577 | 19.1 |
| 2008-2013 | 24,610 | 36.3 | 21,817 | 35.7 | 2,793 | 42.4 | 1,054 | 34.9 |
| Median survival time, years | 2 | 2 | 2 | 1 | ||||
| Median age at death, years | 74 | 74 | 71 | 72 | ||||
| Died from all causes | 46,746 | 69 | 42,648 | 69.8 | 4,098 | 62.1 | 2,293 | 76 |
| Died from multiple myeloma | 33,336 | 49.2 | 30,280 | 49.5 | 3,056 | 46.3 | 1,628 | 54 |
| Died from other cause | 13,410 | 19.8 | 12,368 | 20.2 | 1,042 | 15.8 | 665 | 22 |
| Censored1 | 20,987 | 31 | 18,490 | 30.2 | 2,497 | 37.9 | 725 | 24 |
| Cause-specific death | ||||||||
| Myeloma | 33,336 | 71.3 | 30,280 | 71 | 3,056 | 74.6 | 1,628 | 71.7 |
| Certain infectious and parasitic diseases | 644 | 1.4 | 596 | 1.4 | 48 | 1.2 | 34 | 1.5 |
| Diseases of the circulatory system | 5,360 | 11.5 | 4,948 | 11.6 | 412 | 10.0 | 121 | 5.3 |
| Diseases of the genitourinary system | 692 | 1.5 | 642 | 1.5 | 50 | 1.2 | 42 | 1.8 |
| Diseases of the nervous system | 141 | 0.3 | 134 | 0.3 | 7 | 0.2 | 13 | 0.6 |
| Diseases of the respiratory system | 1,142 | 2.4 | 1,057 | 2.5 | 85 | 2.1 | 85 | 3.7 |
| Endocrine, nutritional and metabolic diseases | 382 | 0.8 | 320 | 0.7 | 62 | 1.5 | 40 | 1.8 |
| Other cancer2 | 2,443 | 5.2 | 2,255 | 5.3 | 188 | 4.6 | 254 | 11.2 |
| Other causes of death3 | 2,606 | 5.6 | 2,416 | 5.7 | 190 | 4.6 | 54 | 2.4 |
SEER = Surveillance, Epidemiology, and End Results.
Alive as of December 2013 or lost to follow-up.
US SEER included malignant neoplasms, stated or presumed to be primary, of lymphoid, hematopoietic and related tissue (n=611, 25%) and malignant neoplasms of independent (primary) multiple sites (n=448, 18%); Puerto Rico include malignant neoplasm of ill-defined, secondary and unspecified sites (n=61, 24%) and malignant neoplasms, stated or presumed to be primary, of lymphoid, hematopoietic and related tissue (n=60, 23%).
US SEER included unspecified other causes of death (n=1,953, 74%) and accidents/adverse events (n=298, 11.4%); Puerto Rico include diseases of digestive system (n=19, 35%) and symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (n=18, 33%), and accidents/adverse events (n=12, 22%).
All p-values for the comparisons between non-Hispanic SEER, Hispanic SEER and Puerto Rico populations were <0.02