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. 2019 Aug 21;11:7877–7891. doi: 10.2147/CMAR.S207834

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© 2019 Wang et al.

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EIF3B activates the PI3K/AKT/mTOR signaling pathway.

Notes: (A) GSEA analyses indicated that high expression of EIF3B was significantly correlated with the mTORC1 pathway in TCGA and GSE21983 datasets. (B) Western blot results of PI3K, AKT, p-AKT, mTOR and p-mTOR expression in EIF3B stable knockdown cells. GAPDH was used as an internal control.