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The IC50 values of anlotinib on osteosarcoma cell lines
| Cell lines | Control | miR-596 | miR-596 + SurvivinMut | miR-596 + inhibitor |
|---|---|---|---|---|
| IC50 values (μmol/L) of anlotinib | ||||
| U2OS | 0.66±0.11 | 0.21±0.02 | 0.58±0.15 | 0.49±0.08 |
| PDC-1 | 0.75±0.22 | 0.15±0.01 | 0.70±0.20 | 0.55±0.10 |
| PDC-2 | 0.80±0.25 | 0.28±0.05 | 0.78±0.23 | 0.65±0.13 |
| PDC-3 | 0.65±0.30 | 0.10±0.03 | 0.67±0.33 | 0.56±0.15 |
| PDC-4 | 0.71±0.33 | 0.20±0.04 | 0.53±0.25 | 0.60±0.07 |
| PDC-5 | 0.75±0.10 | 0.35±0.02 | 0.72±0.24 | 0.63±0.14 |
Abbreviation: PDC, patient-derived cells.
