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The IC50 values of Doxorubicin on osteosarcoma cell lines
| Cell lines | Control | miR-596 | miR-596 + SurvivinMut | miR-596 + inhibitor |
|---|---|---|---|---|
| IC50 values (μmol/L) of doxorubicin | ||||
| U2OS | 0.25±0.04 | 0.05±0.01 | 0.19±0.01 | 0.22±0.04 |
| PDC-1 | 0.40±0.10 | 0.06±0.02 | 0.30±0.05 | 0.25±0.03 |
| PDC-2 | 0.35±0.06 | 0.10±0.02 | 0.33±0.10 | 0.26±0.05 |
| PDC-3 | 0.41±0.12 | 0.21±0.05 | 0.36±0.08 | 0.35±0.02 |
| PDC-4 | 0.50±0.03 | 0.08±0.01 | 0.48±0.05 | 0.40±0.03 |
| PDC-5 | 0.15±0.00 | 0.01±0.00 | 0.10±0.01 | 0.12±0.01 |
Abbreviation: PDCs, patient-devived cells.
