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Results of the meta-analysis of BNP changes for breast cancer patients. SMD were available in 4 studies for a total of 172 patients. The pooled SMD was −0.233 (95% CI −1.113, −0.057). The heterogeneity among studies was not high (I2 = 27.9%, P = .164). The pooled estimated SMD for all studies showed obvious significant difference (z = 3.99, P = .000). BNP = brain natriuretic peptide, SMD = standard mean difference.
