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. 2019 Jul 26;98(30):e16439. doi: 10.1097/MD.0000000000016439

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Copyright © 2019 the Author(s). Published by Wolters Kluwer Health, Inc.

This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0

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Forest plots and funnel plots for the risk ratio of overall treatment-related adverse events. (A1) Forest plots for the risk ratio of overall treatment-related adverse events (PD-1/PD-L1 + chemotherapy vs. chemotherapy). (A2) Funnel plots for the risk ratio of overall treatment-related adverse events (PD-1/PD-L1 + chemotherapy vs. chemotherapy). (B1) Forest plots for the risk ratio of overall treatment-related adverse events (PD-1/PD-L1 vs. chemotherapy). (B2) Funnel plots for the risk ratio of overall treatment-related adverse events (PD-1/PD-L1 vs. chemotherapy). (C1) Forest plots for the risk ratio of overall treatment-related adverse events (nivolumab vs. nivolumab + ipilimumab). (C2) Funnel plots for the risk ratio of overall treatment-related adverse events (nivolumab vs. nivolumab + ipilimumab). PD-1 = programmed cell death 1, PD-L1 = programmed cell death ligand 1.