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. 2019 Aug 8;6(4):ENEURO.0035-19.2019. doi: 10.1523/ENEURO.0035-19.2019

Figure 3.

Figure 3.

CMV-Gpr88 and A2AR-Gpr88 but not D1R-Gpr88 mice show altered defensive burying and social behavior. When placed in the presence of 20 marbles CMV-Gpr88 (A) and A2AR-Gpr88 (C) mice buried less marbles than control animals. D1R-Gpr88 mice (B) show similar numbers of buried marbles compared to control animals. To test social behaviors all mice where left in the presence of a naive wild-type congener and nose contact was counted. Once again, both CMV-Gpr88 (D) and A2AR-Gpr88 (F) mice but not D1R-Gpr88 mice (E) showed increased number of nose contacts compared to their littermates. Data are represented as mean ± SEM. A, D, n = 8 CMV-CTL, n = 10 CMV-Gpr88. B, E, N = 14 D1R-CTL, N = 10 D1R-Gpr88. C, F, n = 10 A2AR-CTL; n = 10 A2AR-Gpr88. Black stars: one star p < 0.05 (Welch’s t test).