Figure 1.

Chronically-implanted optic fibers enable light delivery to V1, ACC, and dHC. Optic fibers (200 µm in diameter; illustrated by the black rectangle) were implanted for delivery of 450-nm wavelength “blue” light to stimulate PV-INs, resulting in the suppression of excitatory output. The expected volume of suppression is a region of tissue 1.5 mm in diameter (illustrated by the blue circle; Weible et al., 2014). AP: anterior (+) or posterior (–) to bregma; DV: ventral to the cortical surface; ML: lateral to the midline.