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Schematic representation of synthesis of GL and GL-AmB by EDC–NHS coupling (A). Ultraviolet spectra of nanoparticles and AmB (2 mg/mL) in H2O and DMSO (B). TEM image of GNP (C, i) and GL-AmB (C, ii). Double arrow indicates the visible layer of AmB on GNP. Selected area electron diffraction pattern indicating presence of GNP in GL-AmB (C, iii).
Abbreviations: EDC, 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide; GNP, gold nanoparticle; NHS, sulfo-N-hydroxy succinamide.
